Overview of the therapeutic possibilities of combined oral contraceptive containing estradiol valerate and dienogest
نویسندگان
چکیده
منابع مشابه
An overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest
Natural estrogens such as estradiol (E(2)) or its valerate ester (E(2)V) offer an alternative to ethinyl estradiol (EE). E(2)-containing combined oral contraceptives (COCs) have demonstrated sufficient ovulation inhibition and acceptable contraceptive efficacy. However, earlier formulations were generally associated with unacceptable bleeding profiles. Two E(2)V-containing preparations have bee...
متن کاملEstradiol valerate and estradiol valerate/dienogest (natazia) tablets: the first four-phasic oral contraceptive.
614 P&T® • November 2010 • Vol. 35 No. 1
متن کاملNoncontraceptive benefits of the estradiol valerate/dienogest combined oral contraceptive: a review of the literature
Combined oral contraceptives formulated to include estradiol (E2) have recently become available for the indication of pregnancy prevention. A combined estradiol valerate and dienogest pill (E2V/DNG), designed to be administered using an estrogen step-down and a progestin step-up regimen over 26 days of active treatment followed by 2 days of placebo (26/2-day regimen), has also undergone resear...
متن کاملEndometrial safety of an oral contraceptive containing estradiol valerate and dienogest
BACKGROUND The purpose of this study was to investigate the endometrial safety of an oral contraceptive containing estradiol valerate/dienogest (E(2)V/DNG) administered as an estrogen step-down and progestogen step-up regimen in women of reproductive age (18-50 years), using histological assessment of endometrial biopsy samples. METHODS Endometrial biopsies were taken in a subset of healthy w...
متن کاملReview of the safety, efficacy and patient acceptability of the combined dienogest/estradiol valerate contraceptive pill
The aim of this review is to define the role of the combined dienogest (DNG)/estradiol valerate (E2V) contraceptive pill, in terms of biochemistry, metabolic and pharmacological effects and clinical application as well. E2V is the esterified form of 17β-estradiol (E2), while dienogest is a fourth-generation progestin with a partial antiandrogenic effect. The cycle stability is achieved with 2 t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Council
سال: 2019
ISSN: 2658-5790,2079-701X
DOI: 10.21518/2079-701x-2019-7-39-44